BCL2L13 Recombinant antibody, PBS Only

BCL2L13 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 86183-1-PBS
Clone No.250705F1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Bcl2-L-13, Bcl-2-like protein 13, Bcl-rambo, CD003, MIL 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

86183-1-PBS targets BCL2L13 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen BCL2L13 fusion protein Ag9841 Predict reactive species
Full Name BCL2-like 13 (apoptosis facilitator)
Calculated Molecular Weight 485 aa, 53 kDa
Observed Molecular Weight 85 kDa
GenBank Accession NumberBC003032
Gene Symbol BCL2L13
Gene ID (NCBI) 23786
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9BXK5
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

BCL2L13/MIL1 gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. BLC2L13 gene is highest expressed in heart, placenta and pancreas. The encoded protein Bcl-rambo may promote the activation of caspase-3 and apoptosis. The Bcl-rambo cell death activity was induced by its membrane-anchored C-terminal domain and not by the Bcl-2 homology region (PMID: 11262395). Multivariate analysis demonstrated that high expression of BCL2L13 was an independent prognostic factor for in childhood acute lymphoblastic leukemia (PMID: 20109966).

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