Product Information
24958-1-PBS targets BEND2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag21152 Product name: Recombinant human BEND2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 298-645 aa of BC096745 Sequence: FHPNLESGPQMSYGTMSYSTEMKNNCDQDDASASACLTPDFALLPLNILVEVDTNTENSVNTMNRSTLLDSDSGQDSSSSSVCIPPKYGYLGDPKRNVRVLKIHLLAVQNMAKPKQAACYLVRILFSKEILISSSVDIHLKDSQSLDPNKMAALREYLATTFPTCDLHEHGKDWQDCISGINSMIYCLCSEGKSTPKTVRKNKKRTNRVASASADRNDQRGRDGGEGCSWMFQPMNNSKMREKRNLQPNSNAIPEGMREPSTDNPEEPGEAWSYFGRPWRNIRMPCSVLTLAKTKSCASLSARYLIQKLFTKDVLVQSNVYGNLKHGLCALDPNKISALRGLLHIEYV Predict reactive species |
| Full Name | BEN domain containing 2 |
| Calculated Molecular Weight | 799 aa, 88 kDa |
| Observed Molecular Weight | 130-140 kDa |
| GenBank Accession Number | BC096745 |
| Gene Symbol | BEND2 |
| Gene ID (NCBI) | 139105 |
| RRID | AB_3742131 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8NDZ0 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
BEND2 (BEN domain-containing protein 2) is a novel protein that is specifically expressed in spermatogenic cells around the time of meiotic initiation (PMID: 35613276). BEND2 interacted with a number of chromatin-associated proteins-including ZMYM2, LSD1, CHD4, and ADNP- which are components of certain transcription-repressor complexes. In the testis, Bend2 expresses two protein isoforms: the 130 kDa protein corresponds to the full-length BEND2, which displays a slower electrophoretic mobility due to its unusual sequence/structure. The 75 kDa protein corresponds to a smaller version of BEND2 lacking the N-terminus, p80 .
