BMP3 Polyclonal antibody, PBS Only

BMP3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 22188-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis of Recombinant protein using 22188-1-AP (same clone as 22188-1-PBS)

  Recombinant protein were subjected to SDS PAGE followed by western blot with 22188-1-AP (BMP3 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22188-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 22188-1-AP (same clone as 22188-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 22188-1-AP (BMP3 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22188-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 22188-1-AP (same clone as 22188-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 22188-1-AP (BMP3 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22188-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 22188-1-AP (same clone as 22188-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 22188-1-AP (BMP3 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22188-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 22188-1-AP (same clone as 22188-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 22188-1-AP (BMP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22188-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 22188-1-AP (same clone as 22188-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22188-1-AP (BMP3 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22188-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 22188-1-AP (same clone as 22188-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22188-1-AP (BMP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22188-1-PBS in a different storage buffer formulation.

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Product Information

22188-1-PBS targets BMP3 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: BMP3 fusion protein Ag16750
• Full Name: bone morphogenetic protein 3
• Calculated Molecular Weight: 472 aa, 53 kDa
• GenBank Accession Number: BC096269
• Gene Symbol: BMP3
• Gene ID (NCBI): 651
• RRID: AB_2879019
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. BMP3 plays an important role in embryonic development by inducing and patterning early skeletal formation. BMP3 has also been reported as a negative growth regulator in bone marrow progenitor cells through the inhibition of DNA synthesis and proliferation. Additionally, recent studies have revealed that BMP3 contributes to tumor development and progression.