BORC6 Polyclonal antibody

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• BORC6 Polyclonal antibody (33196-1-AP)

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  WB analysis using 33196-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 33196-1-AP (Lyspersin antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

BORC6 Polyclonal Antibody for WB, ELISA

Cat No. 33196-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

BLOC-1-related complex subunit 6, BORCS6, C17orf59, Lysosome-dispersing protein, Lyspersin

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Tested Applications

• Positive WB detected in: HEK-293 cells, HeLa cells, RT-4 cells, U-251 cells, U-87 MG cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

33196-1-AP targets BORC6 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag37224

  Product name: Recombinant human C17orf59 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-223 aa of BC018880

  Sequence: MDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPPIDPEVLRDLERLSRELGGRVDRLLRGLGGAVQELTALSVGCIQTYRDAVDSLGEAVDMSIKGMYTLLARCEELERALQPVQGLARQVRDIRRTLEVLEALCK

• Full Name: chromosome 17 open reading frame 59
• Calculated Molecular Weight: 357 aa, 37 kDa
• Observed Molecular Weight: 40 kDa
• GenBank Accession Number: BC018880
• Gene Symbol: C17orf59
• Gene ID (NCBI): 54785
• RRID: AB_3742890
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q96GS4
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

BORC6 is a part of the BORC complex, which may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PMID: 25898167).