BRCA2 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 19791-1-AP

Featured Product KD/KO validated

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Con: 20 μg/150 μl

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Species specificity:
human, rat, mouse

Positive WB detected in:
human brain tissue, HeLa cells

Positive IHC detected in:
rat brain tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
breast cancer 2, early onset

Calculated molecular weight:
384 kDa

Observed molecular weight:
384 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BRCA2

Synonyms
BRCA2, BRCC2, breast cancer 2, early onset, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1
Background

BRCA2, also named as FACD and FANCD1, is involved in double-strand break repair and/or homologous recombination. BRCA2 may participate in S phase checkpoint activation. Defects in BRCA2 are a cause of genetic susceptibility to breast cancer (BC) which also called susceptibility to familial breast-ovarian cancer type 2 (BROVCA2).


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