Rat C-Reactive Protein/CRP Recombinant monoclonal antibody, PBS Only

• 

  WB analysis of rat liver using 83741-3-RR (same clone as 83741-3-PBS)

  rat liver tissue were subjected to SDS PAGE followed by western blot with 83741-3-RR (C-Reactive Protein/CRP antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83741-3-PBS in a different storage buffer formulation.

• 

  IHC staining of rat liver using 83741-3-RR (same clone as 83741-3-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 83741-3-RR (C-Reactive Protein/CRP antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83741-3-PBS in a different storage buffer formulation.

• 

  IHC staining of rat liver using 83741-3-RR (same clone as 83741-3-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 83741-3-RR (C-Reactive Protein/CRP antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83741-3-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 83741-3-RR

  Biolayer interferometry (BLl) kinetic assays of 83741-3-RR against Rat Crp were performed. The affinity constant is below 1 pM.

C-Reactive Protein/CRP Uni-rAb^® Recombinant Antibody for WB, IHC, ELISA

Cat No. 83741-3-PBS

Clone No.240759B8

Host / Isotype

Rabbit / IgG

Reactivity

rat

Applications

WB, IHC, ELISA

Synonyms

PTX1, PTX 1, CRP, 240759B8

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Product Information

83741-3-PBS targets C-Reactive Protein/CRP in WB, IHC, ELISA applications and shows reactivity with rat samples.

• Tested Reactivity: rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: C-reactive protein, pentraxin-related
• Calculated Molecular Weight: 25 kDa
• Observed Molecular Weight: 25 kDa
• GenBank Accession Number: NM_017096.3
• Gene Symbol: Crp
• Gene ID (NCBI): 25419
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P48199
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein belonging to the pentraxin family. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.