CTC1 Polyclonal antibody

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• KD/KO Validated

CTC1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 28268-1-AP

Synonyms

AAF 132, C17orf68, CST complex subunit CTC1, CTC1, FLJ22170

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Validation Data Gallery

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  WB analysis using 28268-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 28268-1-AP (C17orf68 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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  WB analysis of HeLa using 28268-1-AP

  WB result of C17orf68 antibody (28268-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-C17orf68 transfected HeLa cells.

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Tested Applications

• Positive WB detected in: A549 cells, HeLa cells, K562 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

28268-1-AP targets CTC1 in WB, ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: CTC1 fusion protein Ag28167
• Full Name: chromosome 17 open reading frame 68
• Calculated Molecular Weight: 1217 aa, 135 kDa
• Observed Molecular Weight: 135-150 kDa
• GenBank Accession Number: BC111783
• Gene Symbol: C17orf68
• Gene ID (NCBI): 80169
• RRID: AB_2918152
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Conserved telomere maintenance component 1 (CTC1) is a subunit of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase, the enzyme that initiates DNA replication (PMID: 19119139). CTC1 also functions in a telomere-associated complex with STN1 and TEN1 (PMID: 19854130).