Product Information
32175-1-PBS targets C1QL3 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag37280 Product name: Recombinant human C1QL3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 91-140 aa of BC127716 Sequence: GEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGY Predict reactive species |
| Full Name | complement component 1, q subcomponent-like 3 |
| Calculated Molecular Weight | 27 kDa |
| Observed Molecular Weight | 70 kDa, 27 kDa |
| GenBank Accession Number | BC127716 |
| Gene Symbol | C1QL3 |
| Gene ID (NCBI) | 389941 |
| RRID | AB_3742535 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q5VWW1 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
C1Q-like (C1QL) proteins bind to the adhesion G protein coupled receptor B3 (ADGRB3) and act at synapses in a subset of circuits. Complement C1q-like 3 (C1QL3, also known as CTRP13) is one of the C1QL proteins. Some C1QL3 migrated as a monomer (~26 kDa) and some as a trimer (60-70 kDa), indicating a desired substantial yet incomplete crosslinking of monomers (PMID: 33337553). The doublet band of trimer probably represents differential posttranslational modifications (PMID: 21378161). Bands of larger molecular weights suggested either trimers cross-linked into higher molecular weight oligomers or C1QL3 cross-linked to binding partners (PMID: 33337553).
