C3orf62 Polyclonal antibody, PBS Only

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• C3orf62 Polyclonal antibody, PBS Only (32718-1-PBS)

C3orf62 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 32718-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

Uncharacterized protein C3orf62

• 

  WB analysis using 32718-1-AP (same clone as 32718-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32718-1-AP (C3orf62 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32718-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of mouse testis using 32718-1-AP (same clone as 32718-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 32718-1-AP (C3orf62 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32718-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of mouse testis using 32718-1-AP (same clone as 32718-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 32718-1-AP (C3orf62 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32718-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of rat testis using 32718-1-AP (same clone as 32718-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat testis tissue slide using 32718-1-AP (C3orf62 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32718-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of rat testis using 32718-1-AP (same clone as 32718-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat testis tissue slide using 32718-1-AP (C3orf62 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32718-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Product Information

32718-1-PBS targets C3orf62 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag37728

  Product name: Recombinant human C3orf62 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-267 aa of BC023586

  Sequence: MHYIKTWSLLGEMSEKLRRCRKELTAAIDRAFEGVSYSQECTGQQRLELSAAPLSFSLPVHRLLCRRHPLAACSSAAPFAAVPCAPENENPAFATNHAPVNAKPHALCPERKPLTSKENVLMHSSILAPERESWRTAGEGENWRKENLRKDMERDLKADSNMPLNNSSQEVTKDLLDMIDHTSIRTIEELAGKIEFENELNHMCGHCQDSPFKEEAWALLMDKSPQKATDADPGSLKQAFDDHNIVETVLDLEEDYNVMTSFKYQIE

• Full Name: chromosome 3 open reading frame 62
• Calculated Molecular Weight: 30 kDa
• Observed Molecular Weight: 38 kDa
• GenBank Accession Number: BC023586
• Gene Symbol: C3orf62
• Gene ID (NCBI): 375341
• RRID: AB_3742721
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q6ZUJ4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Arrest-type spermatogenic failure refers to the arrest of spermatogenesis at a specific stage, such as spermatogonia, spermatocytes, or spermatids. It is mainly caused by genetic factors, particularly variants in key spermatogenic genes (e.g., TEX11, MSH5, C3ORF62, MEI1, etc.), and represents one of the most distinctive forms of male infertility (PMID: 41669890). The C3orf62 is essential for normal spermatogenesis and male fertility (PMID: 33064489; 38175751).