C8A Polyclonal antibody
C8A Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Cat no : 25289-1-AP
|Positive WB detected in
|Western Blot (WB)
|WB : 1:1000-1:8000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
25289-1-AP targets C8A in WB, ELISA applications and shows reactivity with human samples.
|Host / Isotype
|Rabbit / IgG
|C8A fusion protein Ag18389
|complement component 8, alpha polypeptide
|Calculated molecular weight
|584 aa, 65 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. Complement component C8 alpha chain (C8A) is a constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. Mutations in the C8A gene cause complement C8 alpha-gamma deficiency.