C8A Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 25289-1-AP

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Transfected HEK-293 cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
complement component 8, alpha polypeptide

Calculated molecular weight:
584aa,65 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
C8A

Synonyms
C8A
Background

C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. Complement component C8 alpha chain (C8A) is a constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. Mutations in the C8A gene cause complement C8 alpha-gamma deficiency.


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