CADM1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14335-1-AP

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Freight/Packing

Con: 24 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse liver tissue, A549 cells, human placenta tissue, mouse lung tissue

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cell adhesion molecule 1

Calculated molecular weight:
49 kDa

Observed molecular weight:
49-60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CADM1

Synonyms
BL2, CADM1, cell adhesion molecule 1, DKFZp686F1789, IGSF4, IGSF4A, Necl 2, NECL2, Nectin like protein 2, RA175, sgIGSF, ST17, sTSLC 1, SYNCAM, synCAM1, TSLC 1, TSLC1
Background

CADM1 (cell adhesion molecule 1), also referred to as SgIGSF, Necl-2 or TSLC-1, is a cell adhesion molecule belonging to the immunoglobulin superfamily. It can mediate homophilic and heterophilic cell-cell adhesion. CADM1 is expressed by a variety of cells including neurons, mast cells, spermatogonia, pancreatic islet cells, epithelial cells such as lung alveolar cells and biliary epithelial cells. CADM1 is involved in carcinoma pathogenesis and the expression of CADM1 is frequently down-regulated in various tumors derived from epithelial cells. It acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. (PMID: 18332875; 17326163; 20340131)


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