CBX1 Polyclonal antibody, PBS Only

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• CBX1 Polyclonal antibody, PBS Only (31108-1-PBS)

• 

  WB analysis using 31108-1-AP (same clone as 31108-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31108-1-AP (CBX1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31108-1-PBS in a different storage buffer formulation.

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  WB analysis of MCF-7 using 31108-1-AP (same clone as 31108-1-PBS)

  WB result of CBX1 antibody (31108-1-AP; 1:15000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CBX1 transfected MCF-7 cells. This data was developed using the same antibody clone with 31108-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

CBX1 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 31108-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

CBX, Chromobox protein homolog 1, Heterochromatin protein p25, HP1 beta, HP1Hs beta

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Product Information

31108-1-PBS targets CBX1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag34901

  Product name: Recombinant human CBX1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 60-115 aa of BC002609

  Sequence: CPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFAR

• Full Name: chromobox homolog 1 (HP1 beta homolog Drosophila )
• Calculated Molecular Weight: 27 kDa
• Observed Molecular Weight: 21-27 kDa
• GenBank Accession Number: BC002609
• Gene Symbol: CBX1
• Gene ID (NCBI): 10951
• RRID: AB_3669859
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: P83916
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CBX1 (chromobox 1), also known as CBX. It is expected to be located in nucleus, the protein is expressed in all adult and embryonic tissues. It is a member of the heterochromatin protein family. CBX1 is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. It may play an important role in the epigenetic control of chromatin structure and gene expression. The calculated molecular weight of CBX1 is 21 kDa.