CBX3 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 11650-2-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, A375 cells, mouse spleen tissue

Positive IP detected in:
mouse spleen tissue

Positive IHC detected in:
human colon cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chromobox homolog 3 (HP1 gamma homolog, Drosophila)

Calculated molecular weight:
21 kDa

Observed molecular weight:
22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CBX3

Synonyms
CBX3, Chromobox protein homolog 3, HECH, HP1 GAMMA, HP1Hs gamma, Modifier 2 protein
Background

The family of Heterochromatin protein 1 (HP1) proteins is a family of highly conserved heterochromatin-associated non-histone chromosomal proteins , which has important functions in nucleus. These functions include gene activation or repression, regulation of binding of cohesion complexes to centromere, sequestration of genes to nuclear periphery, and heterochromatin formation and propagation. Much evidence shows that HP1 proteins interact with numerous proteins including methylated histones, histone methyltransferases and so on. CBX3 is one of the paralogues of HP1 proteins


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