CCL20/MIP-3 alpha Recombinant antibody, PBS Only

CCL20/MIP-3 alpha Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA

Cat No. 84413-3-PBS
Clone No.241694B4

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

CCL20, MIP-3 Alpha, MIP-3α, 241694B4, Beta-chemokine exodus-1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

84413-3-PBS targets CCL20/MIP-3 alpha in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen CCL20/MIP-3 alpha fusion protein Eg2398 Predict reactive species
Full Name chemokine (C-C motif) ligand 20
Calculated Molecular Weight11kDa
Observed Molecular Weight11 kDa
GenBank Accession NumberNM_004591.3
Gene Symbol CCL20/MIP-3 alpha
Gene ID (NCBI) 6364
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP78556-1
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.

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