Mouse CD147 Recombinant antibody, PBS Only

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  FC experiment of mouse thymocytes using 98229-1-RR (same clone as 98229-1-PBS)

  1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CD147 Rabbit Recombinant Antibody (98229-1-RR, Clone: 241852B4) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98229-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse thymocytes using 98229-1-RR (same clone as 98229-1-PBS)

  1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CD147 Rabbit Recombinant Antibody (98229-1-RR, Clone: 241852B4) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98229-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98229-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98229-1-RR against Mouse CD147 were performed. The affinity constant is below 1 pM.

CD147 {ptg:Brand} Recombinant Antibody for FC

Cat No. 98229-1-PBS

Clone No.241852B4

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

Membrane glycoprotein gp42, HT7 antigen, Bsg, Basigin, Basic immunoglobulin superfamily

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Product Information

98229-1-PBS targets CD147 in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: basigin
• Calculated Molecular Weight: 42kDa
• GenBank Accession Number: NM_009768.2
• Gene Symbol: CD147
• Gene ID (NCBI): 12215
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P18572-1
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

CD147, also known as Basigin or extracellular matrix metalloproteinase inducer (EMMPRIN), is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 7812975). The molecule is composed of an intracellular portion, an extracellular portion and a single transmembrane region. CD147 is expressed on a variety of cell types (e.g., hematopoietic, epithelial, and endothelial cells) and at varying levels (PMID: 32968061). CD147 is a pleiotropic molecule that plays an important role in fetal, neuronal, lymphocyte and extracellular matrix development (PMID: 17945211).