Anti-Human CD157 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of human peripheral blood leukocytes using 98146-1-RR (same clone as 98146-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.15 ug Anti-Human CD157 Rabbit Recombinant Antibody (98146-1-RR, Clone: 241424H5), or Isotype Control and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed. This data was developed using the same antibody clone with 98146-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98146-1-RR (same clone as 98146-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.15 ug Anti-Human CD157 Rabbit Recombinant Antibody (98146-1-RR, Clone: 241424H5) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed. This data was developed using the same antibody clone with 98146-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98146-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98146-1-RR against Human CD157 were performed. The affinity constant is below 1 pM.

CD157 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98146-1-PBS

Clone No.241424H5

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

BST 1, Bone marrow stromal antigen 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, ADP-ribosyl cyclase 2, ADP ribosyl cyclase 2

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Product Information

98146-1-PBS targets CD157 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant Protein

• Full Name: bone marrow stromal cell antigen 1
• Calculated Molecular Weight: 318 aa, 36 kDa
• GenBank Accession Number: BC012095
• Gene Symbol: CD157
• Gene ID (NCBI): 683
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q10588
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CD157, also known as bone marrow stromal cell antigen 1 (BST-1), or ADP-ribosyl cyclase 2, is a glycosyl phosphotidylinositol-anchored protein that stimulates pre-B-cell growth and has adenosine diphosphate (ADP)-ribosyl cyclase and cyclic ADP-ribose (cADPR) hydrolase activity (PMID: 9473467, 11866528). The two enzymatic activities are responsible for the synthesis and hydrolysis of cADPR, a novel second messenger of calcium release from intracellular calcium stores.