Anti-Human CD160 Rabbit Recombinant Antibody

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  FC experiment of human peripheral blood leukocytes using 98111-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD160 Rabbit Recombinant Antibody (98111-1-RR, Clone: 241415F2) (right) or 0.25 ug Isotype Control (left) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98111-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98111-1-RR against Human CD160 were performed. The affinity constant is 1.81 nM.

CD160 {ptg:Brand} Recombinant Antibody for FC

Cat No. 98111-1-RR

Clone No.241415F2

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

NK1, CD160 molecule, CD160 antigen, soluble form, CD160 antigen, BY55

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Tested Applications

• Positive FC detected in: human peripheral blood leukocytes

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98111-1-RR targets CD160 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant Protein
• Full Name: CD160 molecule
• Calculated Molecular Weight: 20 kDa
• GenBank Accession Number: BC014465
• Gene Symbol: CD160
• Gene ID (NCBI): 11126
• RRID: AB_3672258
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: O95971
• Storage Buffer: PBS with 0.09% sodium azide , pH 7.3
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

CD160 is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed on almost all intestinal intraepithelial lymphocytes (IELs), gamma delta T cells, CD56 (dim) CD16+ cytotoxic NK cells, and a minor subset of CD4+ and CD8+ T cells (PMID: 31332204; 25179432). The binding of CD160 to both classical and non-classical MHC I enhances NK and CD8+ cytotoxic T lymphocyte functions (PMID: 25179432). CD160 is a ligand for HVEM (herpes virus entry mediator) and the binding of CD160 to HVEM inhibits T cell activity (PMID: 19426226).