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Anti-Human CD1a Rabbit Recombinant Antibody, PBS Only (98643-1-PBS)

Anti-Human CD1a Rabbit Recombinant Antibody, PBS Only

Name: Anti-Human CD1a Rabbit Recombinant Antibody, PBS Only, 1mg
Brand: Proteintech
SKU: 98643-1-PBS-1MG

CD1a Uni-rAb^® Recombinant Antibody for FC

Cat No. 98643-1-PBS

Clone No.251904D12

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

CD1, CD1a molecule, FCB6, HTA1, hTa1 thymocyte antigen

Formulation: PBS Only

PBS, Azide

PBS Only

Conjugate: Unconjugated

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Filter: AllFCAffinity

FC experiment of MOLT-4 using 98643-1-RR (same clone as 98643-1-PBS)
1x10^6 MOLT-4 cells were surface stained with 0.25 ug Anti-Human CD1a Rabbit RecAb (98643-1-RR, Clone: 251904D12) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed. This data was developed using the same antibody clone with 98643-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 MOLT-4 cells were surface stained with 0.25 ug Anti-Human CD1a Rabbit RecAb (98643-1-RR, Clone: 251904D12) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed. This data was developed using the same antibody clone with 98643-1-PBS in a different storage buffer formulation.
FC experiment of human monocyte-derived mature dendritic cells using 98643-1-RR (same clone as 98643-1-PBS)
1x10^6 human monocyte-derived mature dendritic cells were surface stained with 0.25 ug Anti-Human CD1a Rabbit RecAb (98643-1-RR, Clone: 251904D12) (red), or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98643-1-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 human monocyte-derived mature dendritic cells were surface stained with 0.25 ug Anti-Human CD1a Rabbit RecAb (98643-1-RR, Clone: 251904D12) (red), or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98643-1-PBS in a different storage buffer formulation.
Affinity and Kinetic Characterization of 98643-1-RR
Biolayer interferometry (BLl) kinetic assays of 98643-1-RR against Human CD1a were performed. The affinity constant is 11.8 nM.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

98643-1-PBS targets CD1a in FC applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	DNA Predict reactive species
Full Name	CD1a molecule
Calculated Molecular Weight	327 aa, 37 kDa
GenBank Accession Number	BC031645
Gene Symbol	CD1a
Gene ID (NCBI)	909
RRID	AB_3746240
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	P06126
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

CD1a is an antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface.