|Positive FC detected in||mouse splenocytes|
|This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.|
|Sample-dependent, check data in validation data gallery|
65104-1-Ig targets CD4 in FC applications and shows reactivity with Mouse samples.
|Host / Isotype||Rat / IgG2b|
|Immunogen||Mouse CTL clone V4|
|Full Name||CD4 antigen|
|GenBank accession number||BC039137|
|Gene ID (NCBI)||12504|
|Purification Method||Affinity purification|
|Storage Buffer||Phosphate based buffer with 0.09% sodium azide, pH 7.2.|
|Storage Conditions||Store at 2-8°C.|
CD4 is a 55-kDa transmembrane glycoprotein expressed on T helper cells, majority of thymocytes, monocytes, macrophages, and dendritic cells (PMID: 9304802; 12213222). CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It plays an important role in T helper cell development and activation (PMID: 9539765; 3112582). CD4 serves as a receptor for the human immunodeficiency virus (HIV) (PMID: 9304802).