Product Information
65654-1-PBS targets CD71 in FC applications and shows reactivity with mouse samples.
Tested Reactivity | mouse |
Host / Isotype | Rat / IgG2a |
Class | Recombinant |
Type | Antibody |
Immunogen | N/A Predict reactive species |
Full Name | transferrin receptor |
GenBank Accession Number | BC054522 |
Gene Symbol | CD71 |
Gene ID (NCBI) | 22042 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule, creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.