Mouse CD79b Recombinant monoclonal antibody, PBS Only

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  WB analysis using 84523-4-RR (same clone as 84523-4-PBS)

  Raji cells were subjected to SDS PAGE followed by western blot with 84523-4-RR (CD79b antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84523-4-PBS in a different storage buffer formulation.

• 

  WB analysis using 84523-4-RR (same clone as 84523-4-PBS)

  Mouse spleen tissue was subjected to SDS PAGE followed by western blot with 84523-4-RR (CD79b antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84523-4-PBS in a different storage buffer formulation.

• 

  WB analysis using 84523-4-RR (same clone as 84523-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84523-4-RR (CD79b antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84523-4-PBS in a different storage buffer formulation.

CD79b Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 84523-4-PBS

Clone No.241850G7

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

Immunoglobulin-associated B29 protein, Ig-beta, Igb, B-cell-specific glycoprotein B29, B-cell antigen receptor complex-associated protein beta chain

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Product Information

84523-4-PBS targets CD79b in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  FusionProtein

• Full Name: CD79B antigen
• Calculated Molecular Weight: 26 kDa
• Observed Molecular Weight: 36-40 kDa
• GenBank Accession Number: NM_008339.3
• Gene Symbol: Cd79b
• Gene ID (NCBI): 15985
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P15530
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).