CD79b Recombinant antibody

• 

  WB analysis using 84523-4-RR

  Raji cells were subjected to SDS PAGE followed by western blot with 84523-4-RR (CD79b antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 84523-4-RR

  Mouse spleen tissue was subjected to SDS PAGE followed by western blot with 84523-4-RR (CD79b antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 84523-4-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84523-4-RR (CD79b antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

CD79b Recombinant Antibody for WB, ELISA

Cat No. 84523-4-RR

Clone No.241850G7

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Synonyms

Immunoglobulin-associated B29 protein, Ig-beta, Igb, B-cell-specific glycoprotein B29, B-cell antigen receptor complex-associated protein beta chain

---

Tested Applications

• Positive WB detected in: Raji cells, mouse spleen tissue, Ramos cells, Daudi cells

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:16000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

84523-4-RR targets CD79b in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: FusionProtein
• Full Name: CD79B antigen
• Calculated Molecular Weight: 26 kDa
• Observed Molecular Weight: 36-40 kDa
• GenBank Accession Number: NM_008339.3
• Gene Symbol: Cd79b
• Gene ID (NCBI): 15985
• RRID: AB_3672031
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P15530
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).