FcZero-rAb® APC-Cyanine7 Anti-Human CD79b Rabbit Recombinant Antibody

• Home
• Products
• Primary Antibodies
• Flow Cytometry Antibodies
• FcZero-rAb® APC-Cyanine7 Anti-Human CD79b Rabbit Recombinant Antibody (AY7-FcA98075)

• Zero Fc receptor binding
• Site-specific conjugation
• One universal isotype

CD79b FcZero-rAb^® Recombinant Antibody for FC

Cat No. AY7-FcA98075 Copied!

Clone No. 241273B7

Download datasheet

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

B29, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig beta, IGB

• 

  FC experiment of human PBMCs using AY7-FcA98075

  1x10^6 human PBMCs were surface stained with CoraLite® Plus 488 Anti-Human CD19, and 5 ul APC-Cyanine7 Anti-Human CD79b Rabbit RecAb (AY7-FcA98075, Clone: 241273B7) or Rabbit IgG Isotype Control RecAb (AY7-FcA98136, Clone: 240953C9). Cells were incubated with MonoZero™ Monocytes blocking Reagent (PF00020) prior to staining. Cells were not fixed.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  FC experiment of human PBMCs using AY7-FcA98075

  1x10^6 human PBMCs were surface stained with 5 ul APC-Cyanine7 Anti-Human CD79b Rabbit RecAb (AY7-FcA98075, Clone: 241273B7) (red) or Rabbit IgG Isotype Control RecAb (AY7-FcA98136, Clone: 240953C9) (blue). Cells were incubated with MonoZero™ Monocytes blocking Reagent (PF00020) prior to staining. Cells were not fixed.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

Able AI

What's the best dilution for CD79b in ?

Chat with Able

---

Tested Applications

• Positive FC detected in: human PBMCs

Recommended dilution

• Flow Cytometry (FC): FC : 5 ul per 10^6 cells in a 100 µl suspension

This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.

Sample-dependent, Check data in validation data gallery.

Product Information

AY7-FcA98075 targets CD79b in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant Protein

• Full Name: CD79b molecule, immunoglobulin-associated beta
• Calculated Molecular Weight: 229 aa, 26 kDa
• GenBank Accession Number: BC032651
• Gene Symbol: CD79B
• Gene ID (NCBI): 974
• RRID: AB_3746691
• Conjugate: APC-Cyanine7 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 650 nm / 778 nm
• Excitation Laser: Red Laser (633 nm)
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P40259
• Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
• Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).