FcZero-rAb® CoraLite® Plus 647 Anti-Human CD94 Rabbit Recombinant Antibody

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• FcZero-rAb® CoraLite® Plus 647 Anti-Human CD94 Rabbit Recombinant Antibody (CL647-FcA98172)

• Zero Fc receptor binding
• Site-specific conjugation
• One universal isotype

CD94 FcZero-rAb^® Recombinant Antibody for FC

Cat No. CL647-FcA98172 Copied!

Clone No. 241704E11

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

Killer cell lectin-like receptor subfamily D member 1, KLRD1, KP43, NK cell receptor

• 

  FC experiment of human PBMCs using CL647-FcA98172

  1x10^6 human PBMCs were surface stained with CoraLite® Plus 405 Anti-Human NCAM1/CD56, and 5 ul CoraLite® Plus 647 Anti-Human CD94 Rabbit RecAb (CL647-FcA98172, Clone: 241704E11) or FcZero-rAb® CoraLite® Plus 647 Rabbit IgG Isotype Control Recombinant Antibody (CL647-FcA98136, Clone: 240953C9). Cells were not fixed. Lymphocytes were gated.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  FC experiment of human PBMCs using CL647-FcA98172

  1x10^6 human PBMCs were surface stained with 5 ul CoraLite® Plus 647 Anti-Human CD94 Rabbit RecAb (CL647-FcA98172, Clone: 241704E11) (red) or FcZero-rAb® CoraLite® Plus 647 Rabbit IgG Isotype Control Recombinant Antibody (CL647-FcA98136, Clone: 240953C9) (blue). Cells were not fixed. Lymphocytes were gated.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive FC detected in: human PBMCs

Recommended dilution

• Flow Cytometry (FC): FC : 5 ul per 10^6 cells in a 100 µl suspension

This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.

Sample-dependent, Check data in validation data gallery.

Product Information

CL647-FcA98172 targets CD94 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant Protein

• Full Name: killer cell lectin-like receptor subfamily D, member 1
• Calculated Molecular Weight: 179 aa, 20 kDa
• GenBank Accession Number: BC028009
• Gene Symbol: CD94
• Gene ID (NCBI): 3824
• Conjugate: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 654 nm / 674 nm
• Excitation Laser: Red Laser (633 nm)
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q13241
• Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
• Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

CD94, also known as the killer cell lectin-like receptor (KLR) family member, is a type II integral membrane protein related to the C-type lectin superfamily. It is specifically expressed on natural killer (NK) cells and a subset of T cells, and plays a crucial role in stimulating NK cell cytolysis and the release of tumor necrosis factor. CD94 can form heterodimers with different NKG2 proteins (e.g., NKG2A, NKG2C, NKG2E, or NKG2F) to balance the function of NK cells and CD8+ T cells.