Anti-Human CEACAM8/CD66b Rabbit Recombinant Antibody

CEACAM8/CD66b Uni-rAb^TM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

230353B7

Cat no : 98012-1-RR

Synonyms

CD66b, CEACAM8, CD 67, CD 66b, Carcinoembryonic antigen-related cell adhesion molecule 8

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Validation Data Gallery

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  FC experiment of human peripheral blood leukocytes using 98012-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM8/CD66b Rabbit Recombinant Antibody (98012-1-RR, Clone:230353B7) or 0.25 ug Isotype Control, and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed.

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  Affinity and Kinetic Characterization of 98012-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98012-1-RR against Human CEACAM8/CD66b were performed. The affinity constant is 2.31 nM.

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Tested Applications

• Positive FC detected in: human peripheral blood leukocytes

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98012-1-RR targets CEACAM8/CD66b in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: carcinoembryonic antigen-related cell adhesion molecule 8
• Calculated Molecular Weight: 38 kDa
• GenBank Accession Number: BC026263
• Gene Symbol: CEACAM8
• Gene ID (NCBI): 1088
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS with 0.09% sodium azide.
• Storage Conditions: Store at 2-8°C. Stable for one year after shipment.

Background Information

Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8), also known as CD66b, CGM6 or NCA-95, is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAM8 is a glycosylphosphatidylinositol (GPI)-linked glycoprotein expressed on granulocytes (PMID: 8104998; 18056392). It is involved in regulating adhesion and activation of eosinophils (PMID: 18056392).