CER1 Polyclonal antibody, PBS Only

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• CER1 Polyclonal antibody, PBS Only (18879-1-PBS)

• 

  WB analysis using 18879-1-AP (same clone as 18879-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18879-1-AP (CER1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18879-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse kidney using 18879-1-AP (same clone as 18879-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse kidney tissue using CER1 antibody (18879-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 18879-1-PBS in a different storage buffer formulation.

CER1 Polyclonal Antibody for WB, IF-P, Indirect ELISA

Cat No. 18879-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF-P, Indirect ELISA

Synonyms

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Product Information

18879-1-PBS targets CER1 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag12926

  Product name: Recombinant human CER1 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1-267 aa of BC069405

  Sequence: MHLLLFQLLVLLPLGKTTRHQDGRQNQSSLSPVLLPRNQRELPTGNHEEAEEKPDLFVAVPHLVGTSPAGEGQRQREKMLSRFGRFWKKPEREMHPSRDSDSEPFPPGTQSLIQPIDGMKMEKSPLREEAKKFWHHFMFRKTPASQGVILPIKSHEVHWETCRTVPFSQTITHEGCEKVVVQNNLCFGKCGSVHFPGAAQHSHTSCSHCLPAKFTTMHLPVNCTELSSVIKVVMLVEECQCKVKTEHEDGHILHAGSQDSFIPGVSA

• Full Name: cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
• Calculated Molecular Weight: 267 aa, 30 kDa
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: BC069405
• Gene Symbol: CER1
• Gene ID (NCBI): 9350
• RRID: AB_3085568
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O95813
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CER1 is a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. CER1 can exist as homo- or heterodimers (PMID: 23717584, 9501024).