CoraLite® Plus 488-conjugated CES1 Monoclonal antibody
CES1 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-67079
|Positive IF detected in
|IF : 1:50-1:500
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL488-67079 targets CES1 in IF applications and shows reactivity with Human samples.
|Host / Isotype
|Mouse / IgG1
|CES1 fusion protein Ag10647
|carboxylesterase 1 (monocyte/macrophage serine esterase 1)
|Calculated molecular weight
|566 aa, 62 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite® Plus 488 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|493 nm / 522 nm
|Protein G purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
CES1(liver carboxylesterase 1) is also named as CES2, SES1 and belongs to the type-B carboxylesterase/lipase family. The deduced 567-amino acid protein contains a putative 18-amino acid signal peptide and a characteristic C-terminal endoplasmic reticulum retention signal (HXEL). It is the major hydrolytic enzyme responsible for the metabolism of numerous therapeutic agents as well as endogenous substrates.Westernblot analysis demonstrated that CES1 is expressed in human liver microsomes (HLM) but not in human intestinal microsomes (HIM)(PMID:19185566).