Properdin/PFC Monoclonal antibody, PBS Only

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  WB analysis of Jurkat using 66788-1-Ig (same clone as 66788-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 66788-1-Ig (CFP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66788-1-PBS in a different storage buffer formulation.

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  WB analysis of human plasma using 66788-1-Ig (same clone as 66788-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 66788-1-Ig (CFP antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66788-1-PBS in a different storage buffer formulation.

Properdin/PFC Monoclonal Antibody for WB, Indirect ELISA

Cat No. 66788-1-PBS

Clone No.1D5A9

Host / Isotype

Mouse / IgG1

Reactivity

human, rat, pig

Applications

WB, Indirect ELISA

Synonyms

CFP, PFC, complement factor properdin, Complement factor P, BFD

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Product Information

66788-1-PBS targets Properdin/PFC in WB, Indirect ELISA applications and shows reactivity with human, rat, pig samples.

• Tested Reactivity: human, rat, pig
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: Properdin/PFC fusion protein Ag9798
• Full Name: complement factor properdin
• Calculated Molecular Weight: 469 aa, 51 kDa
• Observed Molecular Weight: 50 kDa, 100 kDa, 150 kDa
• GenBank Accession Number: BC015756
• Gene Symbol: CFP
• Gene ID (NCBI): 5199
• RRID: AB_2882133
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• UNIPROT ID: P27918
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105). In plasma, properdin exists as dimers, trimers or tetramers.