Properdin/PFC Monoclonal antibody

Properdin/PFC Monoclonal Antibody for WB, ELISA
Cat No. 66788-1-Ig
Clone No.1D5A9

Host / Isotype

Mouse / IgG1

Reactivity

human, rat, pig

Applications

WB, ELISA

CFP, PFC, complement factor properdin, Complement factor P, BFD

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
CoraLite® Plus 488
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inJurkat cells, human plasma

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

66788-1-Ig targets Properdin/PFC in WB, ELISA applications and shows reactivity with human, rat, pig samples.

Tested Reactivity human, rat, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Properdin/PFC fusion protein Ag9798 Predict reactive species
Full Name complement factor properdin
Calculated Molecular Weight 469 aa, 51 kDa
Observed Molecular Weight 50 kDa, 100 kDa, 150 kDa
GenBank Accession NumberBC015756
Gene Symbol CFP
Gene ID (NCBI) 5199
RRIDAB_2882133
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP27918
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105). In plasma, properdin exists as dimers, trimers or tetramers.

Protocols

Product Specific Protocols
WB protocol for Properdin/PFC antibody 66788-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...