CFP Monoclonal antibody

CFP Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, pig, rat

Applications

WB,ELISA

Conjugate

Unconjugated

CloneNo.

1D5A9

Cat no : 66788-1-Ig

Synonyms

BFD, CFP, Complement factor P, complement factor properdin, PFC, PFD, PROPERDIN



Tested Applications

Positive WB detected inJurkat cells, human plasma tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Sample-dependent, check data in validation data gallery

Product Information

66788-1-Ig targets CFP in WB,ELISA applications and shows reactivity with Human, pig, rat samples.

Tested Reactivity Human, pig, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen CFP fusion protein Ag9798
Full Name complement factor properdin
Calculated molecular weight 469 aa, 51 kDa
Observed molecular weight 50 kDa, 100 kDa, 150 kDa
GenBank accession numberBC015756
Gene symbol CFP
Gene ID (NCBI) 5199
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105). In plasma, properdin exists as dimers, trimers or tetramers.

Protocols

Product Specific Protocols
WB protocol for CFP antibody 66788-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols