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Tested Applications
| Positive WB detected in | mouse cerebellum tissue, mouse brain tissue, mouse testis tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
87798-1-RR targets Claudin 25 in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | claudin-like |
| Calculated Molecular Weight | 229aa, 25 kDa |
| Observed Molecular Weight | 32 kDa |
| GenBank Accession Number | M_001101389 |
| Gene Symbol | hCG_1646420 |
| Gene ID (NCBI) | 644672 |
| RRID | AB_3745756 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | C9JDP6 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Claudin-25, also known as Claudin containing domain 1, is a tight junction protein. It plays a role in epithelial cell barrier function and ion transport regulation. Predominantly expressed in the blood-brain barrier (BBB) and myelin sheaths, it regulates paracellular permeability. It plays vital roles in maintaining neural homeostasis, and its dysregulation is linked to demyelinating diseases and certain cancers.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Claudin 25 antibody 87798-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
