Claudin 25 Recombinant monoclonal antibody, PBS Only

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• Claudin 25 Recombinant monoclonal antibody, PBS Only (87798-1-PBS)

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  WB analysis using 87798-1-RR (same clone as 87798-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 87798-1-RR (CLDN25 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87798-1-PBS in a different storage buffer formulation.

Claudin 25 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 87798-1-PBS

Clone No.253383C11

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

Claudin-25, CLDN25, Putative claudin-25

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Product Information

87798-1-PBS targets Claudin 25 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: claudin-like
• Calculated Molecular Weight: 229aa, 25 kDa
• Observed Molecular Weight: 32 kDa
• GenBank Accession Number: M_001101389
• Gene Symbol: hCG_1646420
• Gene ID (NCBI): 644672
• RRID: AB_3745756
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: C9JDP6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Claudin-25, also known as Claudin containing domain 1, is a tight junction protein. It plays a role in epithelial cell barrier function and ion transport regulation. Predominantly expressed in the blood-brain barrier (BBB) and myelin sheaths, it regulates paracellular permeability. It plays vital roles in maintaining neural homeostasis, and its dysregulation is linked to demyelinating diseases and certain cancers.