CLEC18A Polyclonal antibody, PBS Only

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• CLEC18A Polyclonal antibody, PBS Only (21013-1-PBS)

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  WB analysis of HeLa using 21013-1-AP (same clone as 21013-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 21013-1-AP (CLEC18A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 21013-1-AP (same clone as 21013-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 21013-1-AP (CLEC18A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 21013-1-AP (same clone as 21013-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 21013-1-AP (same clone as 21013-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach using 21013-1-AP (same clone as 21013-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach using 21013-1-AP (same clone as 21013-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach using 21013-1-AP (CLEC18A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 21013-1-PBS in a different storage buffer formulation.

CLEC18A Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 21013-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

MRLP2, MRCL1, MRCL, Mannose receptor-like protein 2, C-type lectin domain family 18 member A

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Product Information

21013-1-PBS targets CLEC18A in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag15237

  Product name: Recombinant human CLEC18A protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 97-446 aa of BC141808

  Sequence: ASGLWRTLQVGWNMQLLPAGLASFVEVVSLWFAEGQRYSHAAGECARNATCTHYMQLVWATSSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFHTCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKRQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWNDQRCKTRNRYICQFAQEHISRWGPGS

• Full Name: C-type lectin domain family 18, member A
• Calculated Molecular Weight: 446 aa, 50 kDa
• Observed Molecular Weight: 47-50 kDa
• GenBank Accession Number: BC141808
• Gene Symbol: CLEC18A
• Gene ID (NCBI): 348174
• RRID: AB_10732842
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: A5D8T8
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CLEC18A, or C-type lectin member 18A, is a protein that plays a significant role in the human immune system, particularly in the context of viral infections. CLEC18A is widely expressed, with the highest levels found in myeloid cells and the liver. It is a co-receptor for TLR3 (Toll-like receptor 3) and is involved in enhancing the host's immune response to viral infections, such as H5N1 influenza A virus (IAV). CLEC18A has been implicated in the development of mixed cryoglobulinemia (MC), an extrahepatic manifestation associated with hepatitis C virus (HCV). This antibody can recognize CLEC18A/B/C.