CLTB Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10455-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 45 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse thymus tissue, human brain tissue, mouse brain tissue, PC-3 cells

Positive IP detected in:
mouse brain tissue

Positive IF detected in:
HeLa cells, HEK-293 cells, HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
clathrin, light chain (Lcb)

Calculated molecular weight:
23 kDa

Observed molecular weight:
32-38 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CLTB

Synonyms
Clathrin light chain B, clathrin, light chain (Lcb), CLTB, LCB
Background

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. The clathrin molecule has a triskelion shape. Each clathrin triskelion is composed of three identical heavy chains (180 kDa) and three light chains of two types, LCA (CLTA) and LCB (CLTB) (30-40 kDa). The light chain subunits are thought to regulate the formation or disassembly of clathrin coats. (PMID: 2445759; 8374173; 3563513)


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