Product Information
34055-1-PBS targets COLEC12 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag39696 Product name: Recombinant human COLEC12 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 140-433 aa of BC060789 Sequence: QASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTNLQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDFQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENITTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLTSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVIMEEMKLVDSKHGQ Predict reactive species |
| Full Name | collectin sub-family member 12 |
| Calculated Molecular Weight | 82 kDa |
| Observed Molecular Weight | 140 kDa, 90 kDa, 70 kDa, |
| GenBank Accession Number | BC060789 |
| Gene Symbol | COLEC12 |
| Gene ID (NCBI) | 81035 |
| RRID | AB_3743145 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q5KU26 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Colonin-12 (COLEC12), also known as colonin subfamily member 12 or CL-P1, is a pattern recognition receptor belonging to the colonin family. As a scavenger receptor, it plays a role in innate immunity, recognizing pathogen-associated molecular patterns (PAMPs) and damaged self-components. COLEC12 plays a role in pathogen clearance, apoptotic cell recognition, and the regulation of inflammatory responses. COLEC12 is also associated with cardiovascular disease and host defense mechanisms. (PMID: 10224141; 27377710;11564734; 24058540)
