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COPS8/COP9 Polyclonal antibody, PBS Only (10089-2-PBS)

Filter: AllWBIPIHC

WB analysis of HepG2 using 10089-2-AP (same clone as 10089-2-PBS)
WB result of COPS8/COP9 antibody (10089-2-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-COPS8/COP9 transfected HepG2 cells. This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.
WB analysis using 10089-2-AP (same clone as 10089-2-PBS)
Various lysates were subjected to SDS PAGE followed by western blot with 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.
WB analysis of HepG2 using 10089-2-PBS
HepG2 cells were subjected to SDS PAGE followed by western blot with 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:1200 incubated at room temperature for 1.5 hours.
IP experiment of mouse brain using 10089-2-AP (same clone as 10089-2-PBS)
IP result of anti-COPS8/COP9 (IP:10089-2-AP, 4ug; Detection:10089-2-AP 1:500) with mouse brain tissue lysate 3200 ug. This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.
IHC staining of human colon cancer using 10089-2-AP (same clone as 10089-2-PBS)
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.
IHC staining of human colon cancer using 10089-2-AP (same clone as 10089-2-PBS)
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.
IHC staining of mouse brain using 10089-2-AP (same clone as 10089-2-PBS)
Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.
IHC staining of mouse brain using 10089-2-AP (same clone as 10089-2-PBS)
Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10089-2-AP (COPS8/COP9 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.
IHC staining of human gliomas using 10089-2-AP (same clone as 10089-2-PBS)
Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 10089-2-AP (COPS8/COP9 antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.
IHC staining of human gliomas using 10089-2-AP (same clone as 10089-2-PBS)
Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 10089-2-AP (COPS8/COP9 antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 10089-2-PBS in a different storage buffer formulation.

COPS8/COP9 Polyclonal antibody, PBS Only

Name: COPS8/COP9 Polyclonal antibody, PBS Only
Brand: Proteintech
SKU: 10089-2-PBS

COPS8/COP9 Polyclonal Antibody for WB, IHC, IP, ELISA

Cat No. 10089-2-PBS

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, ELISA

Synonyms

COP9, COPS8, CSN8, hCOP9, JAB1-containing signalosome subunit 8

Formulation: PBS Only

PBS, Azide, Glycerol

Conjugate: Unconjugated

Size/Concentration:

-/ -

Freight/Packing: -

Quantity

- +

Request bulk or custom quote

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

10089-2-PBS targets COPS8/COP9 in WB, IHC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity	human, mouse, rat
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag0143 Product name: Recombinant human COPS8 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 14-194 aa of BC003090 Sequence: KKLLDQCENQELEAPGGIATPPVYGQLLALYLLHNDMNNARYLWKRIPPAIKSANSELGGIWSVGQRIWQRDFPGIYTTINAHQWSETVQPIMEALRDATRRRAFALVSQAYTSIIADDFAAFVGLPVEEAVKGILEQGWQADSTTRMVLPRKPVAGALDVSFNKFIPLSEPAPVPPIPNE Predict reactive species
Full Name	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
Calculated Molecular Weight	23 kDa
Observed Molecular Weight	23 kDa
GenBank Accession Number	BC003090
Gene Symbol	COPS8
Gene ID (NCBI)	10920
RRID	AB_2081903
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	Q99627
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

COPS8 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.