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  • KD/KO Validated

CORO1C Polyclonal antibody

CORO1C Polyclonal Antibody for IF, IHC, IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IP, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 14749-1-AP

Synonyms

CORO1C, Coronin 1C, Coronin 3, CRNN4, HCRNN4



Tested Applications

Positive WB detected inmouse heart tissue, human heart tissue, SGC-7901 cells, HeLa cells, mouse skeletal muscle tissue
Positive IP detected inmouse skeletal muscle tissue
Positive IHC detected inhuman cervical cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:10-1:100
Sample-dependent, check data in validation data gallery

Product Information

14749-1-AP targets CORO1C in WB, IP, IHC, IF,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, monkey, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CORO1C fusion protein Ag6488
Full Name coronin, actin binding protein, 1C
Calculated molecular weight 53 kDa
Observed molecular weight 57 kDa
GenBank accession numberBC002342
Gene symbol CORO1C
Gene ID (NCBI) 23603
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
WB protocol for CORO1C antibody 14749-1-APDownload protocol
IHC protocol for CORO1C antibody 14749-1-APDownload protocol
IF protocol for CORO1C antibody 14749-1-APDownload protocol
IP protocol for CORO1C antibody 14749-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IHC

FEBS Open Bio

CORO1C expression is associated with poor survival rates in gastric cancer and promotes metastasis in vitro.

Authors - Xiao Cheng
  • KD Validated
humanWB

Mol Med Rep

Silencing of MALAT1 inhibits migration and invasion by sponging miR‑1‑3p in prostate cancer cells.

Authors - Xiaofan Dai
WB

Oncol Rep

Knockdown of Coronin-1C disrupts Rac1 activation and impairs tumorigenic potential in hepatocellular carcinoma cells.

Authors - Wang Zhi-Gang ZG
humanWB

Mol Cell Biochem

miR-26 suppresses renal cell cancer via down-regulating coronin-3.

Authors - Xin Jun Wang
human,mouseWB,IHC

J Exp Clin Cancer Res

Coronin-1C is a novel biomarker for hepatocellular carcinoma invasive progression identified by proteomics analysis and clinical validation.

Authors - Wu Long L
humanIHC, WB

Oncol Rep

microRNA‑196a‑3p inhibits cell proliferation and promotes cell apoptosis by targeting ADP ribosylation factor 4 in diffuse large B‑cell lymphoma.

Authors - Jianhong Fu

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Wen (Verified Customer) (12-22-2019)

Work well in western blot

  • Applications: Western Blot,
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: mouse haematopoietic cells