|Positive WB detected in||mouse heart tissue, human heart tissue, SGC-7901 cells, HeLa cells, mouse skeletal muscle tissue|
|Positive IP detected in||mouse skeletal muscle tissue|
|Positive IHC detected in||human cervical cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||HepG2 cells|
|Western Blot (WB)||WB : 1:500-1:3000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Immunofluorescence (IF)||IF : 1:10-1:100|
|Sample-dependent, check data in validation data gallery|
14749-1-AP targets CORO1C in WB, IP, IHC, IF,ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, monkey, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||CORO1C fusion protein Ag6488|
|Full Name||coronin, actin binding protein, 1C|
|Calculated molecular weight||53 kDa|
|Observed molecular weight||57 kDa|
|GenBank accession number||BC002342|
|Gene ID (NCBI)||23603|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
|Product Specific Protocols|
|WB protocol for CORO1C antibody 14749-1-AP||Download protocol|
|IHC protocol for CORO1C antibody 14749-1-AP||Download protocol|
|IF protocol for CORO1C antibody 14749-1-AP||Download protocol|
|IP protocol for CORO1C antibody 14749-1-AP||Download protocol|
|Click here to view our Standard Protocols|
FEBS Open Bio
CORO1C expression is associated with poor survival rates in gastric cancer and promotes metastasis in vitro.
Mol Med Rep
Silencing of MALAT1 inhibits migration and invasion by sponging miR‑1‑3p in prostate cancer cells.
Knockdown of Coronin-1C disrupts Rac1 activation and impairs tumorigenic potential in hepatocellular carcinoma cells.
Mol Cell Biochem
miR-26 suppresses renal cell cancer via down-regulating coronin-3.
J Exp Clin Cancer Res
Coronin-1C is a novel biomarker for hepatocellular carcinoma invasive progression identified by proteomics analysis and clinical validation.
Hum Mol Genet
Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Wen (Verified Customer) (12-22-2019)
Work well in western blot