CP110 Monoclonal antibody

CP110 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human and More (1)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

CloneNo.

1A3C12

Cat no : 66448-1-Ig

Synonyms

Centrosomal protein of 110 kDa, CP110, CP110 protein, KIAA0419



Tested Applications

Positive WB detected inHeLa cells, HEK-293 cells, K-562 cells, Jurkat cells, U2OS cells, HL-60 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

66448-1-Ig targets CP110 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen CP110 fusion protein Ag3489
Full Name CP110 protein
Calculated Molecular Weight 991 aa, 111 kDa
Observed Molecular Weight 110 kDa
GenBank Accession NumberBC036654
Gene Symbol CP110
Gene ID (NCBI) 9738
RRIDAB_2881817
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CP110, also named as CCP110 and KIAA0419, is an 110kDa protein. This gene is different to the gene CEP110 (geneID:11064; CNTRL). CP110 is a centriolar protein that positively regulates centrioleduplication while restricting centriole elongation and ciliogenesis. And it acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.

Protocols

Product Specific Protocols
WB protocol for CP110 antibody 66448-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIHC

Mol Biol Cell

The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic.

Authors - Rachel E Turn
humanIF

Mol Biol Cell

Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E

Authors - Skylar I Dewees