|Positive WB detected in||HeLa cells, HEK-293 cells, K-562 cells, Jurkat cells, U2OS cells, HL-60 cells|
|Western Blot (WB)||WB : 1:1000-1:4000|
|Sample-dependent, check data in validation data gallery|
66448-1-Ig targets CP110 in WB, IHC, ELISA applications and shows reactivity with human samples.
|Host / Isotype||Mouse / IgG2a|
|Immunogen||CP110 fusion protein Ag3489|
|Full Name||CP110 protein|
|Calculated molecular weight||991 aa, 111 kDa|
|Observed molecular weight||110 kDa|
|GenBank accession number||BC036654|
|Gene ID (NCBI)||9738|
|Purification Method||Protein A purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
CP110, also named as CCP110 and KIAA0419, is an 110kDa protein. This gene is different to the gene CEP110 (geneID:11064; CNTRL). CP110 is a centriolar protein that positively regulates centrioleduplication while restricting centriole elongation and ciliogenesis. And it acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.