CP110 Monoclonal antibody, PBS Only

CP110 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A3C12

Cat no : 66448-1-PBS

Synonyms

Centrosomal protein of 110 kDa, CP110, CP110 protein, KIAA0419

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Validation Data Gallery

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  WB analysis using 66448-1-Ig (same clone as 66448-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66448-1-Ig (CP110 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66448-1-PBS in a different storage buffer formulation.

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Recommended dilution

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

66448-1-PBS targets CP110 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: CP110 fusion protein Ag3489
• Full Name: CP110 protein
• Calculated Molecular Weight: 991 aa, 111 kDa
• Observed Molecular Weight: 110 kDa
• GenBank Accession Number: BC036654
• Gene Symbol: CP110
• Gene ID (NCBI): 9738
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

CP110, also named as CCP110 and KIAA0419, is an 110kDa protein. This gene is different to the gene CEP110 (geneID:11064; CNTRL). CP110 is a centriolar protein that positively regulates centrioleduplication while restricting centriole elongation and ciliogenesis. And it acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.