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  • Featured Product
  • KD/KO Validated

CPT1C Monoclonal antibody, PBS Only

CPT1C Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, pig

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

5D11B5

Cat no : 66072-1-PBS

Synonyms

CATL1, CPT IC, CPT1 B, CPT1C, CPT1P, CPTI B, CPTIC

Validation Data Gallery

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  • Western Blot (WB) analysis of human brain tissue using CPT1C Monoclonal antibody (66072-1-Ig)

    WB analysis of human brain using 66072-1-Ig (same clone as 66072-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 66072-1-Ig (CPT1C antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66072-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human testis tissue using CPT1C Monoclonal antibody (66072-1-Ig)

    IHC staining of human testis using 66072-1-Ig (same clone as 66072-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human testis using 66072-1-Ig(CPT1C antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66072-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human testis tissue using CPT1C Monoclonal antibody (66072-1-Ig)

    IHC staining of human testis using 66072-1-Ig (same clone as 66072-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human testis using 66072-1-Ig(CPT1C antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66072-1-PBS in a different storage buffer formulation.

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

66072-1-PBS targets CPT1C in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig samples.

Tested Reactivity human, pig
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen CPT1C fusion protein Ag17963
Full Name carnitine palmitoyltransferase 1C
Calculated Molecular Weight 792 aa, 90 kDa
Observed Molecular Weight 82 kDa
GenBank Accession NumberBC029104
Gene Symbol CPT1C
Gene ID (NCBI) 126129
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CPT1C, also named as CATL1, CPTI-B and B-CPTI, belongs to the carnitine/choline acetyltransferase family. Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer (CPT1) and inner (CPT2) mitochondrial membranes. CPT1C is an active forms of related brain-type carnitine palmitoyltransferase I. CPT1C may be a regulated target of malonyl-CoA that relays the "malonyl-CoA signal" in hypothalamic neurons that express the orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. (PMID: 17018521 ) This antibody can bind the close sequences genes.