CoraLite® Plus 488-conjugated CSF1R/CD115 Recombinant antibody

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  IF Staining of THP-1 using CL488-84477-6

  Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using CoraLite® Plus 488 CSF1R/CD115 antibody (CL488-84477-6, Clone: 241675D4 ) at dilution of 1:200.

CSF1R/CD115 Uni-rAb^TM Recombinant Antibody for IF/ICC

Cat No. CL488-84477-6

Clone No.241675D4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

CSF1R, 241675D4, C FMS, CD115, CSF 1 R

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Tested Applications

• Positive IF/ICC detected in: THP-1 cells

Recommended dilution

• Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

CL488-84477-6 targets CSF1R/CD115 in applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant Protein
• Full Name: colony stimulating factor 1 receptor
• Calculated Molecular Weight: 972 aa, 108 kDa
• Observed Molecular Weight: 160 kDa
• GenBank Accession Number: BC047521
• Gene Symbol: CSF1R/CD115
• Gene ID (NCBI): 1436
• Conjugate: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 493 nm / 522 nm
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P07333
• Storage Buffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Background Information

CSF1R (colony-stimulating factor 1 receptor) belongs to the type III protein tyrosine kinase receptor family. CSF1R-mediated signaling is crucial for the differentiation and survival of the mononuclear phagocyte system and macrophages in particular (PMID: 28716061).