Product Information
88063-1-PBS targets CSTF2T in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
| Tested Reactivity | human, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Ag5411 Product name: Recombinant human CSTF2T protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 277-616 aa of BC028239 Sequence: PGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGASRQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS Predict reactive species |
| Full Name | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| Calculated Molecular Weight | 64 kDa |
| Observed Molecular Weight | ~70 kDa |
| GenBank Accession Number | BC028239 |
| Gene Symbol | CSTF2T |
| Gene ID (NCBI) | 23283 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9H0L4 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
CSTF2T is one of the three subunits of the mammalian CSTF complex, primarily expressed in germ cells. It regulates 3' cleavage and polyadenylation of pre-mRNA by recognizing a GU/U-rich element downstream of the proximal poly(A) signal (AAUAAA) of the pre-mRNA precursor. This protein possesses RNA-binding and guanylate transferase activity, and is crucial for regulating mRNA stability and translation efficiency.



