CYB5R3 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 10894-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 27 μg/150 μl

Choose size:

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Species specificity:
human, mouse, pig, rat, hamster

Positive WB detected in:
HepG2 cells, human liver tissue, HeLa cells, A431 cells, MCF-7 cells, human placenta tissue, human lung tissue

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cytochrome b5 reductase 3

Calculated molecular weight:
33 kDa

Observed molecular weight:
30-35 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CYB5R3

Synonyms
B5R, CYB5R3, Cytochrome b5 reductase, cytochrome b5 reductase 3, DIA1, Diaphorase 1, NADH cytochrome b5 reductase 3
Background

CYB5R3, also named as DIA1 and B5R, belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. It plays an essential role in the mitochondrial metabolism by its contribution to cellular redox homeostasis. Overstimulation of CYB5R3 associated with lipid rafts can account for the overshot of plasma membrane-focalized superoxide anion production that triggers the entry of CGN in the irreversible phase of apoptosis.


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