CYP4F11 Recombinant monoclonal antibody, PBS Only

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• CYP4F11 Recombinant monoclonal antibody, PBS Only (88260-1-PBS)

CYP4F11 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 88260-1-PBS

Clone No.260726A10

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

3-hydroxy fatty acids omega-hydroxylase CYP4F11, CYPIVF11, Cytochrome P450 4F11, Docosahexaenoic acid omega-hydroxylase, EC:1.14.14.1

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  WB analysis using 88260-1-RR (same clone as 88260-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 88260-1-RR (CYP4F11 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88260-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Product Information

88260-1-PBS targets CYP4F11 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag2906

  Product name: Recombinant human CYP4F11 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 175-524 aa of BC016853

  Sequence: HDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ

• Full Name: cytochrome P450, family 4, subfamily F, polypeptide 11
• Calculated Molecular Weight: 524 aa, 60 kDa
• Observed Molecular Weight: 57-60 kDa
• GenBank Accession Number: BC016853
• Gene Symbol: CYP4F11
• Gene ID (NCBI): 57834
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9HBI6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CYP4F11, also named as CYPIVF11, belongs to the cytochrome P450 family. It is the lone CYP4F/A enzyme that effectively oxidized 3-hydroxypalmitate. It is the predominant catalyst of this fatty acid oxidation reaction in human liver. CYP4F11 is one of the primary human epidermal keratinocytes. It is positively regulated by multiple signaling pathways in HaCaT keratinocytes, including RXR and JNK signaling pathways. (PMID:19812349)