CYP4F8 Polyclonal antibody, PBS Only

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• CYP4F8 Polyclonal antibody, PBS Only (20011-1-PBS)

• 

  IHC staining of human skin using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

CYP4F8 Polyclonal Antibody for IHC, Indirect ELISA

Cat No. 20011-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Synonyms

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Product Information

20011-1-PBS targets CYP4F8 in IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: cytochrome P450, family 4, subfamily F, polypeptide 8
• Calculated Molecular Weight: 60 kDa
• GenBank Accession Number: NM_007253
• Gene Symbol: CYP4F8
• Gene ID (NCBI): 11283
• RRID: AB_2878634
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P98187
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CYP4F8, also named as CPF8, belongs to the cytochrome P450 family. Cytochromes P450 are a group of heme-thiolate monooxygenases. CYP4F8 hydroxylates arachidonic acid (20:4n-6) to (18R)-hydroxyarachidonate. CYP4F8 shows little activity against prostaglandin (PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. CYP4F8 catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid (22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid (22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid (22:5n-6). It catalyzes hydrxylation of PGI2 and carbaprostacyclin. The antibody has no cross reaction to other CYP4F member