Caspase 2/p18 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 24777-1-AP

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Con: 50 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HEK-293 cells, Jurkat cells, mouse kidney tissue

Positive IHC detected in:
human liver cancer tissue,human lung cancer tissue

Positive IF detected in:
HEK-293 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
caspase 2, apoptosis-related cysteine peptidase

Calculated molecular weight:
452aa,51 kDa

Observed molecular weight:
45 kDa,32 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CASP2

Synonyms
CASP 2, CASP2, Caspase 2, Caspase 2/p18, Caspase2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1
Background

CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).


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