Mouse Complement factor D Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 85643-4-RR (same clone as 85643-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85643-4-RR (Cfd antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85643-4-PBS in a different storage buffer formulation.

Complement factor D Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 85643-4-PBS

Clone No.242744B4

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, Indirect ELISA

Synonyms

28 kDa adipocyte protein, Adipsin, Adn, C3 convertase activator, Cfd

---

Product Information

85643-4-PBS targets Complement factor D in WB, Indirect ELISA applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: complement factor D (adipsin)
• Calculated Molecular Weight: 28 kDa
• Observed Molecular Weight: 40-50 kDa
• GenBank Accession Number: NM_013459.4
• Gene Symbol: Cfd
• Gene ID (NCBI): 11537
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P03953-1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Complement factor D, also known as adipsin, is a highly specific serine protease. Complement factor D is the rate-limiting enzyme in the alternative pathway of complement. It activates C3 convertase by cleaving factor B, which is a key step in the alternative pathway. Complement factor D catalyzes the cleavage of factor B to generate Ba (non-catalytic chain) and Bb (active catalytic subunit), which together with C3(H2O) (or C3b) constitute the active C3 convertase C3(H2O)Bb (or C3bBb). (PMID: 34566967; PMID: 27775713).