Product Information
26659-1-PBS targets DENND4A in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag24568 Product name: Recombinant human DENND4A protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1478-1634 aa of BC041706 Sequence: TTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVT Predict reactive species |
| Full Name | DENN/MADD domain containing 4A |
| Observed Molecular Weight | 230 kDa |
| GenBank Accession Number | BC041706 |
| Gene Symbol | DENND4A |
| Gene ID (NCBI) | 10260 |
| RRID | AB_3669559 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q7Z401 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
DENND4A (DENN domain-containing protein 4A), also called IRLB and MYCPBP, is a probable guanine nucleotide exchange factor (GEF) that may activate RAB10. It can promote the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. It may bind to the ISRE-like element (interferon-stimulated response element) of the MYC P2 promoter (PMID: 20937701; 8056341).
