DEPDC6/Deptor Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 20985-1-AP

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 122 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, A2780 cells, COLO 320 cells, HEK-293 cells, MCF-7 cells

Positive IHC detected in:
human liver cancer tissue, human liver cancer tissue, human thyroid cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
DEP domain containing 6

Calculated molecular weight:
46 kDa

Observed molecular weight:
40-45 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DEPDC6

Synonyms
DEP domain containing 6, DEP.6, DEPDC6, Deptor, DKFZp564B1778, FLJ12341, FLJ12428, FLJ13854
Background

DEPDC6, also named as DEPTOR, was identified as a novel mTOR-interacting protein whose over-expression in certain cell types represents a new mechanism for activating PI3K/Akt signaling and promoting cell survival. It negative regulator of the mTORC1 and mTORC2 signaling pathways. DEPDC6 inhibits the kinase activity of both complexes. The antibody is specific to DEPDC6.


Back
to top