Product Information
84671-4-PBS targets DIAPH2 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Ag35280 Product name: Recombinant human DIAPH2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 13-146 aa of NM_006729.4 Sequence: GGSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRITSFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMNLNEEKKAPLRNKDFTTKREMVVQYISAT Predict reactive species |
| Full Name | diaphanous homolog 2 (Drosophila) |
| Calculated Molecular Weight | 126kDa |
| Observed Molecular Weight | 126-130 kDa |
| GenBank Accession Number | NM_006729.4 |
| Gene Symbol | DIAPH2 |
| Gene ID (NCBI) | 1730 |
| RRID | AB_3743650 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O60879 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
In vertebrates, three DRF genes (DIAPH1, DIAPH2 and DIAPH3) are the orthologs of the Drosophila melanogaster diaphanous (dia) gene, which has important roles in fertility and hearing in the fly. DIAPH1 and DIAPH3 have been associated with different types of hearing loss (HL). DIAPH2, located on chromosome Xq21.33, until now it has only been linked to premature ovarian failure 2 (POF2A). (PMID: 36689403)
