DLL4 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21584-1-AP

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Freight/Packing

Con: 33 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue, Transfected HEK-293 cells

Positive IP detected in:
mouse lung tissue

Positive IF detected in:
human stomach cancer tissue

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:150-1:600 for WB
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
delta-like 4 (Drosophila)

Calculated molecular weight:
685aa,75 kDa

Observed molecular weight:
75-80 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DLL4

Synonyms
delta like 4 (Drosophila), Delta like protein 4, Delta4, DLL4, Drosophila Delta homolog 4, hdelta2
Background

DLL4, also named as Delta4, plays a role in the Notch signaling pathway. It activates Notch-1 and Notch-4. Notch signaling is activated upon engagement of the Notch receptor with its ligands, the DSL (Delta, Serrate, Lag2) proteins of single-pass type I membrane proteins. DLL4 is highly expressed in the vascular endothelium.


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